Why choose Fish Scale Collagen?

Why choose Fish Scale Collagen?

Collagen derived from fish scales is described as having better absorption capacity compared to collagens from other sources. Here are the reasons why:

  1. Molecular weight:
    • The molecular weight of the fish scale collagen peptides is rather lower (3000-5000 daltons) than other sources.
    • Small molecules, particularly small peptides, increase the absorption capacity in the digestive tract.
  2. Amino acid profile:
    • The fish collagen consist mainly of hydroxyproline and glycine and proline.
    • That composition is close to that of human collagen and may be welcomed by the body.
  3. Absorption mechanisms:
    • Collagen peptides are primarily absorbed in the small intestine.
    • They can be absorbed intact through specific peptide transporters (like PEPT1).
    • Some are further broken down into individual amino acids before absorption.
  4. Dipeptide advantage:
    • Many fish collagen peptides contain proline-hydroxyproline (Pro-Hyp) dipeptides.
    • These dipeptides have shown higher resistance to further breakdown and can be absorbed intact.
  5. Distribution in the body:
    • Once absorbed, collagen peptides are distributed throughout the body via the bloodstream.
    • Some studies suggest they can accumulate in specific tissues like skin and joints.
  6. Stimulation of collagen synthesis:
    • Absorbed peptides may act as signals, stimulating fibroblasts to produce more collagen.
    • This indirect effect could contribute to the overall benefits of collagen supplementation.
  7. Comparison to other sources:
    • Studies have shown that fish collagen may be absorbed up to 1.5 times more efficiently than bovine or porcine collagen.
  8. Factors affecting bioavailability:
    • The presence of vitamin C can enhance collagen absorption and utilization.
    • Individual factors like age, gut health, and overall diet can also impact absorption.
  9. Time to peak blood levels:
    • Fish collagen peptides typically reach peak levels in the bloodstream within 1-2 hours after ingestion.
  10. Sustained presence:
    • Some studies suggest that collagen peptides can be detected in the blood for up to 14 hours after ingestion, indicating a prolonged effect.

It's important to note that while fish scale collagen shows promising bioavailability, individual responses can vary. More research is still needed to fully understand the long-term impacts and optimal dosing strategies for different health outcomes.

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